Call the Midwife Wiki
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Mrs Franklin was the mother of Nurse Beatrix Aylward.  

Mrs Franklin married a bank manager, and she was likely a housewife, she had three children named Geoffrey, Ronald and Beatrix also known as Trixie. They chose a woman named Daphne to be godmother to Trixie who was likely a close friend of Mrs Franklin. Her husband returned from war suffering from what she called the horrors though would today be called post traumatic stress disorder. She looked after him during the night-time and in the day Trixie and Geoffrey had to make him smile.  

Her husband is definitely dead by the time the series is set but Mrs Franklin is uncertain, she was mentioned by her daughter in S01 E05 when discussing an incestuous relationship between Frank and Peggy Hobson Trixie says she wishes her mother could be as unshockable as Sister Julienne, implying het to be alive at least during the first series. But as her daughters wedding comes in S12 E08 she is nowhere to be seen or even mentioned meaning she is likely deceased by this point.  

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